List of Publicly Traded Mid-Cap Biotech Companies Listed on Major U.S. Exchanges
This list includes mid-sized biotech companies with market capitalizations between two billion and ten billion dollars. We update this page at the start of every month so it is possible that during the course of a month a company’s market cap might fall below two billion or go above ten billion. Additional biotech companies can be found in the following sections:
In parentheses you will find a short description or areas of focus for the company. A comparison widget that shows trend, earnings per share (EPS), P/E ratio and beta for each of the companies on this list can be accessed through the link below.
Mid-Cap Biotech Industry Comparison Widget
Select the company’s link to access charts, news links and company website and social media information.
Biotech: Mid-Cap Stocks
Alnylam Pharmaceuticals, Inc. (ALNY) (Biopharmaceutical company: RNAi therapeutics as genetic medicines; serious, life-threatening diseases)
Bio-Techne Corp (TECH) (Bioactive tools and resources used in the research and clinical diagnostic markets)
China Biologic Products, Inc. (CBPO) (China: plasma-based biopharmaceutical company)
Ionis Pharmaceuticals, Inc. (IONS) (RNA-targeted drug discovery and development: cancer, cardiovascular, metabolic, neurological disorders, rare diseases)
Jazz Pharmaceuticals Plc. (JAZZ) (Ireland, biopharmaceutical company: narcolepsy, lymphoblastic leukemia, hepatic veno-occlusive disease)
Ligand Pharmaceuticals Incorporated (LGND) (Biopharmaceutical company: licensing, royalty-generating assets)
Mallinckrodt Plc. (MNK) (Ireland, biopharmaceutical company: ADHD, autoimmune, central nervous system disorders, pain, rare diseases; medical imaging: contrast media and delivery systems, radiopharmaceuticals)
Nektar Therapeutics (NKTR) (Biopharmaceutical company: anti-infective, anti-viral, immunology, oncology, pain)
TiGenix NV (TIG) (IPO December 15, 2016: biopharmaceutical company, allogeneic stem cell therapies)
Arthritis
Galapagos NV (GLPG) (IPO in May 2015: Belgium: small molecule medicines; rheumatoid arthritis)
Bioinformatics
Qiagen N.V. (QGEN) (Netherlands: Sample & assay technologies: automated systems and consumable products; bioinformatics)
Cancer
Agios Pharmaceuticals, Inc. (AGIO) (Biopharmaceutical company: cancer and rare genetic disorders of metabolism)
Clovis Oncology, Inc. (CLVS) (Biopharmaceutical company: cancer treatments; non-small cell lung cancer, ovarian cancer, pancreatic cancer, breast and lung cancers)
Exelixis, Inc. (EXEL) (Biopharmaceutical company: small molecule therapies used in the treatment of cancer)
Hutchison China MediTech Limited (HCM) (IPO March 17, 2016: Biopharmaceutical company focused on immunological diseases and oncology in addition to consumer health products)
Seattle Genetics, Inc. (SGEN) (Antibody-based therapies for the treatment of cancer)
Tesaro, Inc. (TSRO) (Biopharmaceutical company: oncology therapeutics and supportive care products)
Central Nervous System
ACADIA Pharmaceuticals Inc. (ACAD) (Biopharmaceutical company: central nervous system disorders)
Alkermes Plc. (ALKS) (Ireland, biopharmaceutical company: medicines for the treatment of central nervous system diseases)
Sage Therapeutics, Inc. (SAGE) (Biopharmaceutical company: rare central nervous system disorders)
Liver
Intercept Pharmaceuticals, Inc. (ICPT) (Biopharmaceutical company: orphan and more prevalent liver diseases)
Hemophilia
Bioverativ Inc. (BIVV) (Biotech company: hemophilia and other rare blood disorders)
Neurological
Neurocrine Biosciences, Inc. (NBIX) (Neurological and endocrine based diseases and disorders)
Pain
Horizon Pharma plc (HZNP) (Ireland, biopharmaceutical company: arthritis pain, rare diseases)
Rare Diseases
Bluebird Bio, Inc. (BLUE) (Gene therapy)
Ultragenyx Pharmaceutical Inc. (RARE) (Biopharmaceutical company: debilitating genetic diseases)
Respiratory
United Therapeutics Corporation (UTHR) (Pulmonary arterial hypertension)
Synthetic Biology
Intrexon Corporation (XON) (Products for the consumer, energy, food, health and environmental industries)
Related Links:
List of Pharmaceutical Companies
Publicly Traded Companies by Sector and Industry