Close this search box.

List of Large-Cap Biotech Stocks Listed on U.S. Exchanges

This list includes large-sized biotech companies with market capitalizations of over ten billion dollars. We update this page at the start of every month so it is possible that during the course of a month a stock’s market cap might fall below ten billion dollars. Additional biotech companies can be found in the following sections:

List of Biotech Companies

Mid-Cap Biotech Stocks

Small-Cap Biotech Stocks

Micro-Cap Biotech Stocks

Nano-Cap Biotech Stocks

Molecular Diagnostics

In parentheses you will find a short description or areas of focus for the company. A comparison widget that shows trend, earnings per share (EPS), P/E ratio and beta for each of the companies on this list can be located through selecting the following link:

Large-Cap Biotech Industry Comparison Widget

Select the company’s link to access charts, news links and company website and social media information.

Biotech Companies: Large-Cap Stocks

AbbVie Inc. (ABBV) (Biopharmaceutical company: immunology, kidney disease, liver disease, neuroscience, oncology, women’s health)

Alexion Pharmaceuticals, Inc. (ALXN) (Biopharmaceutical company: nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, hypophosphatasia, Lysosomal Acid Lipase Deficiency)

Amgen Inc. (AMGN) (Therapeutics: cardiovascular, inflammation, oncology, biosimilars)

AstraZeneca Plc. (AZN) (United Kingdom, biopharmaceutical company: autoimmune, cardiovascular, infection, inflammation, metabolic, neuroscience, oncology, respiratory)

Biogen Inc. (BIIB) (Biopharmaceutical company: therapies for immunology, hematology, multiple sclerosis, neurology)

BioMarin Pharmaceutical Inc. (BMRN) (Therapies for serious and life-threatening rare and ultra-rare genetic diseases)

Bristol-Myers Squibb Company (BMY) (Biopharmaceutical company: cancer, cardiovascular disease, hepatitis B and hepatitis C, HIV/AIDS, rheumatoid arthritis)

Celgene Corporation (CELG) (Biopharmaceutical company: cancer and immune-inflammatory related diseases)

Gilead Sciences, Inc. (GILD) (Biopharmaceutical company: cardiovascular, human immunodeficiency virus (HIV), liver diseases, oncology and inflammation, respiratory)

Grifols, S.A. (GRFS) (Spain: Bioscience (treatment of medical conditions using blood or blood components), diagnostics, hospital (intravenous therapy products, clinical nutrition products, sterile products and medical devices), plasma derivatives)

IDEXX Laboratories, Inc. (IDXX) (Diagnostic and information technology-based solutions)

Incyte Corporation (INCY) (Biopharmaceutical company: small molecule drugs; oncology and inflammation)

Regeneron Pharmaceuticals, Inc. (REGN) (Biopharmaceutical company: Antibody technologies; cardiovascular, diabetes, eye diseases, infectious diseases, inflammation, oncology, pain)

Shire Plc. (SHPG) (Ireland, biopharmaceutical company: gastrointestinal, internal medicine, rare diseases, neuroscience)

Vertex Pharmaceuticals Incorporated (VRTX) (Cystic fibrosis; additional ongoing research programs aimed at other serious and life-threatening diseases)

Related Links:

List of Biotech ETFs

List of Pharmaceutical Companies

Publicly Traded Companies by Sector and Industry

List of Healthcare Companies

Large-Cap Stocks