List of Publicly Traded Micro-Cap Biotech Companies Listed on Major U.S. Exchanges

This list includes biotech companies with market capitalizations between 50 million dollars and 300 million dollars. In the world of investing these are referred to as micro-cap stocks. We update this page at the start of every month so it is possible that during the course of a month a company’s market cap might go below 50 million or above 300 million.  Additional biotech companies can be found through the following links:

List of Biotech Companies

Large-Cap Biotech Stocks

Mid-Cap Biotech Stocks

Small-Cap Biotech Stocks

Nano-Cap Biotech Stocks

Molecular Diagnostics

A comparison widget that shows trend, earnings per share (EPS), P/E ratio and beta for each of the companies on this list can be accessed through the link below.

Micro-Cap Biotech Industry Comparison Widget

Select the company’s link to access charts, news links and company website and social media information.

Biotech: Micro-Cap Stocks

Aldeyra Therapeutics, Inc. (ALDX) (Treatments for diseases thought to be related to endogenous free aldehydes)

BioLineRx Ltd. (BLRX) (Israel, biopharmaceutical company: Cardiac device, acute myeloid leukemia, celiac disease, infectious diseases, inflammatory bowel disease, skin lesions)

CorMedix Inc. (CRMD) (Infectious and inflammatory diseases)

Kadmon Holdings, Inc. (KDMN) (IPO July 27, 2016: biopharmaceutical company developing product candidates within autoimmune and fibrotic diseases, oncology and genetic diseases)    

KalVista Pharmaceuticals, Inc. (KALV) (Small molecule protease inhibitors)

Kamada Ltd. (KMDA) (Israel, biopharmaceutical company: specialty therapeutics developed through a protein purification technology)

Madrigal Pharmaceuticals, Inc. (MDGL) (Cardiovascular, liver and metabolic diseases)

Reata Pharmaceuticals, Inc. (RETA) (IPO May 26, 2016: biopharmaceutical company focused on developing drugs that modulate the activity of important regulatory proteins)

Trevena, Inc. (TRVN) (Biopharmaceutical company: discovery and development of GPCR biased ligands)

ADHD

Alcobra Ltd. (ADHD) (Israel, biopharmaceutical company: Attention Deficit Hyperactivity Disorder (ADHD) and other cognitive disorders)

Animal Health

Kindred Biosciences, Inc. (KIN) (Biotechnology company that develops medicines for pets)

Anti-Infectives

Cidara Therapeutics, Inc. (CDTX) (IPO in April 2015: Anti-infectives; fungal infections)

Nabriva Therapeutics AG (NBRV) (IPO in September 2015: Austria, biopharmaceutical company: anti-infectives designed to treat bacterial infections)

Antivirals

Chimerix, Inc. (CMRX) (Biopharmaceutical company: oral antivirals)

ContraVir Pharmaceuticals Inc. (CTRV) (Biopharmaceutical company: antiviral therapies; shingles, Hepatitis B virus)

NanoViricides, Inc. (NNVC) (Nanotechnology-based biomimetic anti-viral medicines)

Autoimmune Diseases

Anthera Pharmaceuticals, Inc. (ANTH) (Biopharmaceutical company: inflammation and autoimmune diseases)

Biocatalysts

Codexis, Inc. (CDXS) (Protein engineering company: develops biocatalysts for pharmaceuticals and fine chemicals markets)

Biosimilars

Pfenex Inc. (PFNX) (Non-glycosylated biosimilars)

Cancer

Actinium Pharmaceuticals, Inc. (ATNM) (Biopharmaceutical company: immunotherapeutics for the treatment of advanced cancers)

Aeglea BioTherapeutics, Inc. (AGLE) (IPO April 7, 2016: Biotech company focused therapeutics for the treatment of inborn errors of metabolism (IEM) and cancer)

Affimed N.V. (AFMD) (Germany, biopharmaceutical company: cancer immunotherapies)

Argos Therapeutics, Inc. (ARGS) (Biopharmaceutical company: immunotherapies for the treatment of cancer and infectious diseases)

ArQule, Inc. (ARQL) (Small molecule cancer therapeutics)

AVEO Pharmaceuticals, Inc. (AVEO) (Biopharmaceutical company: therapies through biomarker-driven insights)

Bio-Path Holdings, Inc. (BPTH) (Therapeutic products using its proprietary liposomal delivery technology)

Cascadian Therapeutics Inc. (CASC) (Biopharmaceutical company: cancer treatments)

CASI Pharmaceuticals, Inc. (CASI) (Biopharmaceutical company: therapeutics addressing cancer and other unmet medical needs; focus on China)

Cellular Biomedicine Group, Inc. (CBMG) (Treatments for cancer and degenerative diseases)

Compugen Ltd. (CGEN) (Israel: immuno-oncology programs which are aimed at harnessing the immune system to eradicate cancer)

Concert Pharmaceuticals, Inc. (CNCE) (CNS disorders, renal disease, inflammation and cancer)

CTI BioPharma Corp. (CTIC) (Biopharmaceutical company: therapies covering a spectrum of blood-related cancers)

Diffusion Pharmaceuticals Inc. (DFFN) (Cancer focused biotech company)

Endocyte, Inc. (ECYT) (Biopharmaceutical company: therapies for the treatment of cancer and inflammatory diseases)

Fortress Biotech (FBIO) (Biopharmaceutical company: cancer, additional products in pipeline)

Galena Biopharma, Inc. (GALE) (Biopharmaceutical company: oncology therapeutics across the full spectrum of cancer care)

GTX, Inc. (GTXI) (Small molecules for the treatment of cancer and serious medical conditions)

Ignyta, Inc. (RXDX) (Oncology company)

Immune Design Corp. (IMDZ) (Immunotherapy company)

ImmunoGen, Inc. (IMGN) (Targeted cancer therapeutics)

Infinity Pharmaceuticals, Inc. (INFI) (Biopharmaceutical company: Blood cancers, indolent non-Hodgkin lymphoma, chronic lymphocytic leukemia)

Kura Oncology, Inc. (KURA) (IPO in November 2015: Biopharmaceutical company; therapeutics for the treatment of solid tumors and blood cancers)

MEI Pharma, Inc. (MEIP) (Therapies for the treatment of cancer)

Mirati Therapeutics, Inc. (MRTX) (Oncology company: genetically-targeted oncology therapeutics)

Oncobiologics, Inc. (ONS) (IPO May 13, 2016, biopharmaceutical company: biosimilar therapeutics)

Peregrine Pharmaceuticals Inc. (PPHM) (Biopharmaceutical company: antibodies; treatment and diagnosis of cancer)

Pieris Pharmaceuticals, Inc. (PIRS) (Biotechnology company: areas of focus include cancer, asthma and anemia)

Prima BioMed Ltd (PBMD) (Australia: immunotherapeutic products for the treatment of cancer)

Rigel Pharmaceuticals, Inc. (RIGL) (Small-molecule drugs for the treatment of immune diseases and cancers)

Stemline Therapeutics, Inc. (STML) (Biopharmaceutical company: therapeutics that target cancer stem cells and tumor bulk)

Sunesis Pharmaceuticals, Inc. (SNSS) (Biopharmaceutical company: oncology therapeutics for the potential treatment of solid and hematologic cancers)

Syndax Pharmaceuticals, Inc. (SNDX) (IPO March 3, 2016: Biopharmaceutical company engaged in the development of cancer treatments)

TG Therapeutics, Inc. (TGTX) (Biopharmaceutical company: B-cell malignancies and autoimmune diseases)

Tracon Pharmaceuticals, Inc. (TCON) (IPO in January 2015: Biopharmaceutical company: therapeutics for cancer, age-related macular degeneration and fibrotic diseases)

Trillium Therapeutics Inc. (TRIL) (Canada: immuno-oncology company)

Vascular Biogenics Ltd. (VBLT) (Israel: Treatments for cancer)

Cannabanoid Treatments

Zynerba Pharmaceuticals Inc. (ZYNE) (Synthetic cannabinoid treatments)

Cell Therapies

Asterias Biotherapeutics, Inc. (AST) (Regenerative medicine: therapeutics developed from platforms based on pluripotent stem cells and dendritic cell cancer immunotherapy)

Celyad SA (CYAD) (IPO in June 2015, Belgium: Cell therapy treatments; cardiovascular disease, oncology)

Pluristem Therapeutics, Inc. (PSTI) (Israel: Cell therapies for a broad spectrum of diseases)

Vericel Corporation (VCEL) (Cellular therapies for treatment of severe diseases and conditions)

Central Nervous System

Anavex Life Sciences Corp. (AVXL) (Biopharmaceutical company: Alzheimer’s, other CNS diseases; cancer)

Axsome Therapeutics, Inc. (AXSM) (IPO in November 2015: Biopharmaceutical company: therapies for pan management and central nervous system disorders)

Intec Pharma Ltd. (NTEC) (IPO in August 2015: Israel, biopharmaceutical company: oral drug delivery system, Parkinson’s disease)

Titan Pharmaceuticals, Inc. (TTNP) (Biopharmaceutical company: CNS disorders)

Critical Care

Tenax Therapeutics, Inc. (TENX) (Treatment for various critical care conditions)

Defense

PharmAthene, Inc. (PIP) (Biological and chemical defense products)

Dietary Supplements

Neptune Technologies & Bioresources Inc. (NEPT) (Canada: omega-3 dietary supplements)

Eyes

Adverum Biotechnologies, Inc. (ADVM) (Biopharmaceutical company: serious eye diseases)

Applied Genetic Technologies Corporation (AGTC) (Treatments for rare eye diseases caused by mutated genes)

Clearside Biomedical, Inc. (CLSD) (IPO June 2, 2016: biopharmaceutical company focused on therapies for blinding eye diseases)

Eleven Biotherapeutics, Inc. (EBIO) (Ocular therapeutics to treat patients suffering from eye diseases)

Inotek Pharmaceuticals Corporation (ITEK) (Biopharmaceutical company: therapies to treat glaucoma and other serious diseases of the eye)

NovaBay Pharmaceuticals, Inc. (Biopharmaceutical company: anti-infective treatments, ophthalmology)

Ocular Therapeutix, Inc. (OCUL) (Biopharmaceutical company: therapies for diseases and conditions of the eye through its hydrogel platform technology)

Ohr Pharmaceuticals, Inc. (OHRP) (Ocular diseases)

Ophthotech Corporation (OPHT)  (Biopharmaceutical company: back of the eye diseases)

Fertility

Ovascience Inc. (OVAS) (Life sciences company: treatments for infertility)

Gastrointestinal

Redhill Biopharma Ltd. (RDHL) (Israel, biopharmaceutical company: inflammatory and gastrointestinal diseases, gastrointestinal cancers)

Genomic Medicine

Aevi Genomic Medicine, Inc. (GNMX) (Genomic medicine)

Heart

Capricor Therapeutics, Inc. (CAPR) (Treatment of heart failure and heart attacks)

Gemphire Therapeutics Inc. (GEMP) (IPO August 5, 2016: biopharmaceutical company focused on therapies to treat dyslipidemia)

Immunotherapy

Calithera Biosciences, Inc. (CALA) (Immunotherapy company: cell process optimization, development, and manufacturing)

Infectious Diseases

ADMA Biologics Inc. (ADMA) (Biopharmaceutical company: Plasma-based biologics for the treatment and prevention of certain infectious diseases)

Aviragen Therapeutics, Inc. (AVIR) (Antivirals to treat infections)

ContraFect Corporation (CFRX) (Therapeutic protein and antibody products for infectious diseases)

Dynavax Technologies Corporation (DVAX) (Biopharmaceutical company; products to prevent and treat infectious diseases)

Sangamo BioSciences, Inc. (SGMO) (Biopharmaceutical company: infectious diseases, monogenic diseases, hemoglobinopathies)

Summit Therapeutics Plc. (SMMT) (IPO in March 2015: United Kingdom, biopharmaceutical company: Duchenne Muscular Dystrophy, infectious disease caused by the bacteria C. difficile)

Infections

Motif Bio plc (MTFB) (IPO November 18, 2016: biopharmaceutical company, development of antibiotics for infections)

Inflammation

Ampio Pharmaceuticals, Inc. (AMPE) (Biopharmaceutical company: inflammatory conditions)

Kidney

Aurinia Pharmaceuticals Inc. (AUPH) (Canada, biopharmaceutical company: lupus nephritis)

Liver

Arbutus Biopharma Corporation (ABUS) (Canada, biopharmaceutical company: chronic hepatitis B infection)

Arrowhead Research Corporation (ARWR) (Biopharmaceutical company: RNAi therapeutics, chronic hepatitis B infection)

Assembly Biosciences, Inc. (ASMB) (Biopharmaceutical company: treatments for hepatitis B virus infection and C. difficile-associated diarrhea)

Conatus Pharmaceuticals Inc. (CNAT) (Medicines to treat liver disease)

Dicerna Pharmaceuticals, Inc. (DRNA) (Biopharmaceutical company: inherited diseases of the liver and genetically defined cancers)

Dimension Therapeutics Inc. (DMTX) (IPO in October 2015: Gene therapy platform company: rare diseases associated with the liver)

Ocera Therapeutics, Inc. (OCRX) (Biopharmaceutical company: acute and chronic liver disease)

Vital Therapies, Inc. (VTL) (Cell-based system for the treatment of acute liver failure)

Microbiome

Synthetic Biologics, Inc. (SYN) (Therapeutics to protect the microbiome)

Neurological

MediciNova, Inc. (MNOV) (Biopharmaceutical company: neurological disorders, treatment of acute exacerbations of asthma)

Neuromuscular disorders

Flex Pharma, Inc. (FLKS) (Neuromuscular disorders including muscle cramps)

Nutritional Supplements

Enzymotec Ltd. (ENZY) (Israel: lipid-based products used in infant formula, nutritional supplements, medical disorders and diseases)

Pain

Cara Therapeutics, Inc. (CARA) (Chemical entities designed to alleviate pain and pruritus)

Durect Corporation (DRRX) (Biopharmaceutical company: pain management, CNS disorders, acute organ injury and metabolic diseases)

Rare Diseases

Abeona Therapeutics (ABEO) (Gene therapy and plasma-based products)

Akari Therapeutics, Plc (AKTX) (United Kingdom, biopharmaceutical company: therapeutics to treat orphan autoimmune and inflammatory diseases)

aTyr Pharma Inc. (LIFE) (IPO in May 2015: Medicines used in the treatment of severe rare diseases)

Catabasis Pharmaceuticals Inc. (CATB) (Biopharmaceutical company: rare diseases, serious lipid disorders)

Catalyst Pharmaceutical Partners, Inc. (CPRX) (Biopharmaceutical company: rare neuromuscular and neurological diseases)

Chiasma Inc. (CHMA) (IPO in July 2015, biopharmaceutical company: oral versions of injected drugs for orphan diseases)

Eiger BioPharmaceuticals, Inc. (EIGR) (Biopharmaceutical company: Hepatitis Delta, Hypoglycemia, Pulmonary Arterial Hypertension, Lymphedema)

Fate Therapeutics, Inc. (FATE) (Biopharmaceutical company: cellular immunotherapeutics; cancer, rare genetic diseases and immune disorders)

Idera Pharmaceuticals, Inc. (IDRA) (B-cell Lymphoma, autoimmune, rare)

Novelion Therapeutics Inc. (NVLN) (Rare diseases)

Regulus Therapeutics Inc. (RGLS) (Biopharmaceutical company: microRNA therapeutics for oncology indications and orphan diseases)

Strongbridge Biopharma plc (SBBP) (IPO in October 2015: Biopharmaceutical company; rare endocrine disorders and other rare diseases)

UniQure N.V. (QURE) (Netherlands: gene therapy)

Xenon Pharmaceuticals Inc. (XENE) (Canada, biopharmaceutical company: lipoprotein lipase deficiency)

Regenerative Medicine

Athersys, Inc. (ATHX) (Biopharmaceutical company: most advanced programs in area of regenerative medicine; stem cell products)

Osiris Therapeutics, Inc. (OSIR) (Regenerative products for wound care, sports medicine, and orthopaedics)

Respiratory

ProQR Therapeutics N.V. (PRQR) (Netherlands: Cystic fibrosis and severe genetic disorders)

Sickle Cell disease

GlycoMimetics, Inc. (GLYC) (Vaso-occlusive crisis of sickle cell disease; treatment for AML in combination with chemotherapy)

Urology

Nymox Pharmaceutical Corporation (NYMX) (Drugs and diagnostic products for the aging population; treatment for enlarged prostate or benign prostatic hyperplasia)

Sophiris Bio, Inc. (SPHS) (Biopharmaceutical company: urological diseases)

Vaccines

Genocea Biosciences, Inc. (GNCA) (Vaccines and immunotherapies: infectious diseases, cancers and autoimmune diseases)

VBI Vaccines Inc. (VBIV) (Biopharmaceutical company: vaccines)

Viral Diseases

Spring Bank Pharmaceuticals, Inc. (SBPH) (Biopharmaceutical company: viral diseases)

Weight Management

VIVUS, Inc. (VVUS) (Biopharmaceutical company: weight management, erectile dysfunction)

Zafgen, Inc. (ZFGN) (Biopharmaceutical company: obesity)

Women’s Health

Palatin Technologies, Inc. (PTN) (Biopharmaceutical company: female sexual dysfunction; development programs or drug candidates for other areas)

Wound Care

MediWound Ltd. (MDWD) (Israel, Biopharmaceutical company: severe burns, chronic and other hard-to-heal wounds)